Sexual side effects of SSRI medications: potential treatment strategies for SSRI-induced female sexual dysfunction
- PMID: 12429073
Sexual side effects of SSRI medications: potential treatment strategies for SSRI-induced female sexual dysfunction
Abstract
Depression often coexists with sexual dysfunction, and the medical treatment of depression can further worsen sexual symptoms or cause de novo sexual dysfunction in a person who did not experience it prior to treatment. There are many drugs that can adversely affect sexual response. Among antidepressants, this effect is commonly observed with selective serotonin-reuptake inhibitors (SSRI). Various strategies for the treatment of SSRI-related sexual dysfunction have been studied, including: awaiting spontaneous remission of sexual dysfunction; reducing the dose of medication; taking a "drug holiday"; adding another drug to help reverse sexual symptoms; changing antidepressants; or initially starting with a different antidepressant that is known to have fewer or no sexual side effects. Overall, it is important to address sexual health when caring for a patient--to improve drug compliance and the patient's well being.
Similar articles
-
A double-blind, randomized, pilot dose-finding study of maca root (L. meyenii) for the management of SSRI-induced sexual dysfunction.CNS Neurosci Ther. 2008 Fall;14(3):182-91. doi: 10.1111/j.1755-5949.2008.00052.x. CNS Neurosci Ther. 2008. PMID: 18801111 Free PMC article. Clinical Trial.
-
Effect of buspirone on sexual dysfunction in depressed patients treated with selective serotonin reuptake inhibitors.J Clin Psychopharmacol. 1999 Jun;19(3):268-71. doi: 10.1097/00004714-199906000-00012. J Clin Psychopharmacol. 1999. PMID: 10350034 Clinical Trial.
-
Effect of Vortioxetine vs. Escitalopram on Sexual Functioning in Adults with Well-Treated Major Depressive Disorder Experiencing SSRI-Induced Sexual Dysfunction.J Sex Med. 2015 Oct;12(10):2036-48. doi: 10.1111/jsm.12980. Epub 2015 Aug 31. J Sex Med. 2015. PMID: 26331383 Clinical Trial.
-
Sexual Consequences of Post-SSRI Syndrome.Sex Med Rev. 2017 Oct;5(4):429-433. doi: 10.1016/j.sxmr.2017.05.002. Epub 2017 Jun 20. Sex Med Rev. 2017. PMID: 28642048 Review.
-
[Sexual dysfunction associated with antidepressant agents].Ugeskr Laeger. 2014 May 26;176(22):V11130687. Ugeskr Laeger. 2014. PMID: 25352006 Review. Danish.
Cited by
-
Rosa damascena oil improves SSRI-induced sexual dysfunction in male patients suffering from major depressive disorders: results from a double-blind, randomized, and placebo-controlled clinical trial.Neuropsychiatr Dis Treat. 2015 Mar 9;11:625-35. doi: 10.2147/NDT.S78696. eCollection 2015. Neuropsychiatr Dis Treat. 2015. PMID: 25834441 Free PMC article.
-
Environmental concentrations of the selective serotonin reuptake inhibitor fluoxetine impact specific behaviors involved in reproduction, feeding and predator avoidance in the fish Pimephales promelas (fathead minnow).Aquat Toxicol. 2014 Jun;151:77-83. doi: 10.1016/j.aquatox.2013.10.012. Epub 2013 Oct 16. Aquat Toxicol. 2014. PMID: 24210950 Free PMC article.
-
Pharmacology of serotonin and female sexual behavior.Pharmacol Biochem Behav. 2014 Jun;121:31-42. doi: 10.1016/j.pbb.2013.11.008. Epub 2013 Nov 15. Pharmacol Biochem Behav. 2014. PMID: 24239784 Free PMC article. Review.
MeSH terms
Substances
LinkOut - more resources
Other Literature Sources
Medical