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Table 4 Regression analysis of influencing factors for alpha-fetoprotein abnormal trajectory phenomenon

From: Unusual phenomenon in advanced hepatocellular carcinoma: declining alpha-fetoprotein levels despite disease progression

Factors

Univariate regression analysis

Multivariate regression analysis

P-value

OR (95% CI)

P-value

OR (95% CI)

Sex

0.110

0.34(0.09–1.31)

  

NLR

0.008

1.22(1.05–1.43)

0.025

1.29(1.03–1.62)

Extrahepatic Metastasis

0.450

0.61(0.16–2.22)

  

Major Vascular Invasion

0.340

0.53(0.14–1.94)

  

Child–Pugh Classification

0.520

1.67(0.33–8.23)

  

Treatment Type

    

Targeted Therapy

TACE

0.690

1.78(0.1–30.8)

0.370

4.14(0.18–95.40)

Targeted + Immunotherapy

0.046

9.21(1.04– 81.30)

0.034

15.35(1.22–192.90)

TACE + Targeted + Immunotherapy

0.460

0.35(0.02–5.84)

0.700

0.56(0.03–10.60)