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Comparative Study
. 2000 Nov;26(3):358-61.
doi: 10.1038/81685.

Y chromosome sequence variation and the history of human populations

P A Underhill  1 , P Shen, A A Lin, L Jin, G Passarino, W H Yang, E Kauffman, B Bonné-Tamir, J Bertranpetit, P Francalacci, M Ibrahim, T Jenkins, J R Kidd, S Q Mehdi, M T Seielstad, R S Wells, A Piazza, R W Davis, M W Feldman, L L Cavalli-Sforza, P J Oefner
Affiliations
Comparative Study

Y chromosome sequence variation and the history of human populations

P A Underhill et al. Nat Genet. 2000 Nov.

Abstract

Binary polymorphisms associated with the non-recombining region of the human Y chromosome (NRY) preserve the paternal genetic legacy of our species that has persisted to the present, permitting inference of human evolution, population affinity and demographic history. We used denaturing high-performance liquid chromatography (DHPLC; ref. 2) to identify 160 of the 166 bi-allelic and 1 tri-allelic site that formed a parsimonious genealogy of 116 haplotypes, several of which display distinct population affinities based on the analysis of 1062 globally representative individuals. A minority of contemporary East Africans and Khoisan represent the descendants of the most ancestral patrilineages of anatomically modern humans that left Africa between 35,000 and 89,000 years ago.

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  • The past within us.
    Renfrew C, Forster P, Hurles M. Renfrew C, et al. Nat Genet. 2000 Nov;26(3):253-4. doi: 10.1038/81518. Nat Genet. 2000. PMID: 11062451 No abstract available.

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