Microarray analysis: genome-scale hypothesis scanning
- PMID: 14551912
- PMCID: PMC212694
- DOI: 10.1371/journal.pbio.0000015
Microarray analysis: genome-scale hypothesis scanning
Abstract
Microarrays can survey genome-wide expression patterns. Not only can these gene expression profiles be used to identify a few genes of interest, they are now being creatively applied for hypothesis generation and testing
Figures
Similar articles
-
Tech.Sight. Biochips for gene spotting.Science. 2001 Oct 19;294(5542):621-3. doi: 10.1126/science.294.5542.621. Science. 2001. PMID: 11641502 No abstract available.
-
Microarray-based genome investigation: molecular karyotyping or segmental aneuploidy profiling?Eur J Hum Genet. 2006 Mar;14(3):262-5. doi: 10.1038/sj.ejhg.5201553. Eur J Hum Genet. 2006. PMID: 16391563 No abstract available.
-
Linear RNA amplification for the production of microarray hybridization probes.Methods Mol Biol. 2008;420:303-17. doi: 10.1007/978-1-59745-583-1_19. Methods Mol Biol. 2008. PMID: 18641956
-
Microarray-based DNA profiling to study genomic aberrations.IUBMB Life. 2008 Jul;60(7):437-40. doi: 10.1002/iub.57. IUBMB Life. 2008. PMID: 18553550 Review.
-
From single gene to integrative molecular concept MAPS: pitfalls and potentials of microarray technology.J Biol Regul Homeost Agents. 2008 Jan-Mar;22(1):7-16. J Biol Regul Homeost Agents. 2008. PMID: 18394313 Review.
Cited by
-
PNME - A gene-gene parallel network module extraction method.J Genet Eng Biotechnol. 2018 Dec;16(2):447-457. doi: 10.1016/j.jgeb.2018.08.003. Epub 2018 Dec 11. J Genet Eng Biotechnol. 2018. PMID: 30733759 Free PMC article.
-
Differences in X-chromosome transcriptional activity and cholesterol metabolism between placentae from swine breeds from Asian and Western origins.PLoS One. 2013;8(1):e55345. doi: 10.1371/journal.pone.0055345. Epub 2013 Jan 31. PLoS One. 2013. PMID: 23383161 Free PMC article.
-
Mitochondria, oligodendrocytes and inflammation in bipolar disorder: evidence from transcriptome studies points to intriguing parallels with multiple sclerosis.Neurobiol Dis. 2012 Jan;45(1):37-47. doi: 10.1016/j.nbd.2011.01.025. Epub 2011 Feb 17. Neurobiol Dis. 2012. PMID: 21310238 Free PMC article. Review.
-
Cooperation, conflict, and the evolution of queen pheromones.J Chem Ecol. 2011 Nov;37(11):1263-75. doi: 10.1007/s10886-011-0036-z. Epub 2011 Nov 15. J Chem Ecol. 2011. PMID: 22083225 Review.
-
Regulation by transcription factors in bacteria: beyond description.FEMS Microbiol Rev. 2009 Jan;33(1):133-51. doi: 10.1111/j.1574-6976.2008.00145.x. FEMS Microbiol Rev. 2009. PMID: 19076632 Free PMC article. Review.
References
-
- Alizadeh AA, Eisen MB, Davis RE, Ma C, Lossos IS, et al. Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling. Nature. 2000;403:503–511. - PubMed
-
- Ideker T, Thorsson V, Ranish J, Christmas R, Buhler J, et al. Integrated genomic and proteomic analyses of a systematically perturbed metabolic network. Science. 2001;292:929–934. - PubMed
-
- Toma DP, White KP, Hirsch J, Greenspan RJ. Identification of genes involved in Drosophila melanogaster geotaxis, a complex behavioral trait. Nat Genet. 2002;31:349–353. - PubMed
-
- van't Veer LJ, Dai H, van de Vijver MJ, He YD, Hart AA, et al. Gene expression profiling predicts clinical outcome of breast cancer. Nature. 2002;415:530–536. - PubMed
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources