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Review
. 2007 Oct;17(5):713-8.
doi: 10.1089/cap.2006.0138.

Meta-analysis of aggression and/or hostility-related events in children and adolescents treated with fluoxetine compared with placebo

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Review

Meta-analysis of aggression and/or hostility-related events in children and adolescents treated with fluoxetine compared with placebo

Sitra Tauscher-Wisniewski et al. J Child Adolesc Psychopharmacol. 2007 Oct.

Abstract

This meta-analysis assessed aggression and/or hostility-related events in children and adolescents treated with fluoxetine (n = 376) compared with placebo (n = 255). Aggression and/or hostility-related events were identified in 2.1% of fluoxetine versus 3.1% of placebo-treated patients (p = 0.588). This analysis fails to support an association between fluoxetine treatment and increased risk of aggression and/or hostility-related events in children and adolescents compared with placebo.

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