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Comparative Study
. 2009 May;50(5):637-42.
doi: 10.1111/j.1469-7610.2008.02051.x. Epub 2009 Feb 27.

Visual orienting in the early broader autism phenotype: disengagement and facilitation

Mayada Elsabbagh  1 , Agnes Volein, Karla Holmboe, Leslie Tucker, Gergely Csibra, Simon Baron-Cohen, Patrick Bolton, Tony Charman, Gillian Baird, Mark H Johnson
Affiliations
Comparative Study

Visual orienting in the early broader autism phenotype: disengagement and facilitation

Mayada Elsabbagh et al. J Child Psychol Psychiatry. 2009 May.

Abstract

Background: Recent studies of infant siblings of children diagnosed with autism have allowed for a prospective approach to examine the emergence of symptoms and revealed behavioral differences in the broader autism phenotype within the early years. In the current study we focused on a set of functions associated with visual attention, previously reported to be atypical in autism.

Method: We compared performance of a group of 9-10-month-old infant siblings of children with autism to a control group with no family history of autism on the 'gap-overlap task', which measures the cost of disengaging from a central stimulus in order to fixate a peripheral one. Two measures were derived on the basis of infants' saccadic reaction times. The first is the Disengagement effect, which measures the efficiency of disengaging from a central stimulus to orient to a peripheral one. The second was a Facilitation effect, which arises when the infant is cued by a temporal gap preceding the onset of the peripheral stimulus, and would orient faster after its onset.

Results and conclusion: Infant siblings of children with autism showed longer Disengagement latencies as well as less Facilitation relative to the control group. The findings are discussed in relation to how differences in visual attention may relate to characteristics observed in autism and the broader phenotype.

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Figures

Figure 1
Figure 1
Reaction time data in the three conditions. Scatter plots show individual infant’s scores in each condition. Dark solid bars show the group means. Dotted boxes highlight cases with standardized residuals above 2.5
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References

    1. Bolton P, Macdonald H, Pickles A, Rios P, Goode S, Crowson M, et al. A case–control family history study of autism. Journal of Child Psychology and Psychiatry. 1994;35:877–900. - PubMed
    1. Brown J, Johnson MH, Paterson S, Gilmore R, Gsödl M, Longhi E, Kamiloff-Smith A. Spatial representation and attention in toddlers with Williams syndrome and Down syndrome. Neurosychologia. 2003;41:1037–1046. - PubMed
    1. Bryson SE, Landry R, Czapinski P, Mcconnell B, Rombough V, Wainwright A. Autistic spectrum disorders: Causal mechanisms and recent findings on attention and emotion. International Journal of Special Education. 2004;19:14–22.
    1. Casey BJ, Gordon CT, Mannheim GB, Rumsey JM. Dysfunctional attention in autistic savants. Journal of Clinical and Experimental Neuropsychology. 1993;15:933–946. - PubMed
    1. Charman T, Baird G. Practitioner review: Diagnosis of autism spectrum disorder in 2- and 3-year-old children. Journal of Child Psychology and Psychiatry. 2002;43:289–305. - PubMed

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