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Review
. 2013 Feb;6(1):212-7.
doi: 10.1161/CIRCEP.112.974931.

Increased left ventricular mass as a predictor of sudden cardiac death: is it time to put it to the test?

Steven M Stevens  1 , Kyndaron Reinier, Sumeet S Chugh
Affiliations
Review

Increased left ventricular mass as a predictor of sudden cardiac death: is it time to put it to the test?

Steven M Stevens et al. Circ Arrhythm Electrophysiol. 2013 Feb.
No abstract available

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Figures

Figure 1
Figure 1
Arrhythmogenic mechanisms of sudden cardiac death associated with left ventricular hypertrophy (LVH) and severely reduced left ventricular ejection fraction (EF). These mechanisms are likely to have additive effects in increasing risk of sudden cardiac death (SCD).
Figure 2
Figure 2
(a) Venn diagram demonstrating that current risk stratification for primary prevention ICD is largely based on LV ejection fraction (LVEF) 35%. This approach likely misses the majority of sudden cardiac death (SCD) and patients with Left Ventricular Hypertrophy (LVH) could account for a proportion of that burden. (b) Ideally ICD therapy would prevent more SCD. If LVH determined from the same echo that assesses the LVEF is included in the risk stratification algorithm, it is likely that more high-risk patients would be identified. These would include some patients that have increased cumulative risk (LVH + low LVEF) as well as a sub-group with LVH and preserved LVEF.
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