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. 1989 Sep;171(9):4958-62.
doi: 10.1128/jb.171.9.4958-4962.1989.

Regulation of the Escherichia coli glyA gene by the metR gene product and homocysteine

M D Plamann  1 , G V Stauffer
Affiliations

Regulation of the Escherichia coli glyA gene by the metR gene product and homocysteine

M D Plamann et al. J Bacteriol. 1989 Sep.

Abstract

The methionine component of glyA gene regulation in Escherichia coli K-12 was investigated. The results indicate that the glyA gene is positively controlled by the metR gene product. Activation of glyA by the MetR protein requires homocysteine, an intermediate in methionine biosynthesis. The positive-acting metR regulatory system functions independently of a regulatory system shown previously to control glyA gene expression.

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