Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2018 Apr;8(2):135-141.
doi: 10.1212/CPJ.0000000000000433.

SSRI-associated bruxism: A systematic review of published case reports

Andrew R Garrett  1 , Jason S Hawley  1
Affiliations
Review

SSRI-associated bruxism: A systematic review of published case reports

Andrew R Garrett et al. Neurol Clin Pract. 2018 Apr.

Abstract

Purpose of review: Antidepressant-associated movement disorders are a well-described phenomenon. However, antidepressant-associated bruxism, jaw pain, or jaw spasm, while reported in dental literature, is less commonly recognized among neurologists. We summarize the clinical features and treatment of antidepressant-associated bruxism and associated jaw pain through a systematic review of case reports.

Recent findings: Antidepressant-associated bruxism may occur in pediatric and adult patients, most commonly among female patients. Patients may develop symptoms with short-term and long-term antidepressant use. Fluoxetine, sertraline, and venlafaxine were the most commonly reported offending agents. Symptoms may begin within 3-4 weeks of medication initiation and may resolve within 3-4 weeks of drug discontinuation, addition of buspirone, or substitution with another pharmacologic agent. The incidence of this phenomenon is unknown.

Summary: Bruxism associated with antidepressant use is an underrecognized phenomenon among neurologists, and may be treated with the addition of buspirone, dose modification, or medication discontinuation.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. American Academy of Sleep Medicine. The International Classification of Sleep Disorders: Diagnostic and Coding Manual. 3rd ed Darien, IL: American Academy of Sleep Medicine; 2014.
    1. McAuliffe P. Types of bruxism. J Ir Dent Assoc 2012;58:138–141. - PubMed
    1. Naranjo CA, Busto U, Sellers EM, et al. . A method for estimating the probability of adverse drug reactions. Clin Pharmacol Ther 1981;30:239–245. - PubMed
    1. Shetty S, Pitti V, Satish Babu CL, Surendra Kumar GP, Deepthi BC. Bruxism: a literature review. J Indian Prosthodont Soc 2010;10:141–148. - PMC - PubMed
    1. Uca AU, Uğuz F, Kozak HH, et al. . Antidepressant-induced sleep bruxism: prevalence, incidence, and related factors. Clin Neuropharmacol 2015;38:227–230. - PubMed