Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Book

Left Ventricular Hypertrophy

Abraham B. Bornstein  1 , Suman S. Rao  2 , Komal Marwaha  3
In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
.
Affiliations
Free Books & Documents
Book

Left Ventricular Hypertrophy

Abraham B. Bornstein et al.
Free Books & Documents

Excerpt

Left ventricular hypertrophy (LVH) is a condition in which there is an increase in left ventricular mass, either due to an increase in wall thickness or due to left ventricular cavity enlargement, or both. Most commonly, the left ventricular wall thickening occurs in response to pressure overload, and chamber dilatation occurs in response to the volume overload.

PubMed Disclaimer

Conflict of interest statement

Disclosure: Abraham Bornstein declares no relevant financial relationships with ineligible companies.

Disclosure: Suman Rao declares no relevant financial relationships with ineligible companies.

Disclosure: Komal Marwaha declares no relevant financial relationships with ineligible companies.

References

    1. Cuspidi C, Sala C, Negri F, Mancia G, Morganti A, Italian Society of Hypertension Prevalence of left-ventricular hypertrophy in hypertension: an updated review of echocardiographic studies. J Hum Hypertens. 2012 Jun;26(6):343-9. - PubMed
    1. Marketou ME, Parthenakis F, Vardas PE. Pathological Left Ventricular Hypertrophy and Stem Cells: Current Evidence and New Perspectives. Stem Cells Int. 2016;2016:5720758. - PMC - PubMed
    1. Jia G, Aroor AR, Hill MA, Sowers JR. Role of Renin-Angiotensin-Aldosterone System Activation in Promoting Cardiovascular Fibrosis and Stiffness. Hypertension. 2018 Sep;72(3):537-548. - PMC - PubMed
    1. Sciarretta S, Paneni F, Palano F, Chin D, Tocci G, Rubattu S, Volpe M. Role of the renin-angiotensin-aldosterone system and inflammatory processes in the development and progression of diastolic dysfunction. Clin Sci (Lond) 2009 Mar;116(6):467-77. - PubMed
    1. Marian AJ, Braunwald E. Hypertrophic Cardiomyopathy: Genetics, Pathogenesis, Clinical Manifestations, Diagnosis, and Therapy. Circ Res. 2017 Sep 15;121(7):749-770. - PMC - PubMed

Publication types

LinkOut - more resources